Neutrophil-to-lymphocyte ratio and carbohydrate antigen 19-9 as prognostic markers for advanced pancreatic cancer patients receiving first-line chemotherapy

Table 3 The association of the first response evaluation and post-treatment neutrophil-to-lymphocyte ratio according to carbohydrate antigen 19-9 response in carbohydrate antigen 19-9 positive group

	Decline of CA19-9 ≥ 18%					Decline of CA19-9 < 18%
Post-treatment NLR	< 2.62		≥ 2.62			< 2.62		≥ 2.62
	n = 67	%	n = 38	%	P value1	n = 39	%	n = 75	%	P value1
1st Response					0.002					0.009
CR/PR	35	52.2	10	26.3		4	10.3	5	6.7
SD	29	43.3	21	55.3		21	53.8	21	28.0
PD	3	4.5	7	18.4		14	35.9	49	65.3

¹P value from linear-by-linear association test. NLR: Neutrophil-to-lymphocyte ratio; CA19-9: Carbohydrate antigen 19-9; CR: Complete response; PR: Partial response; SD: Stable disease; PD: Progressive disease.