Role of exosomal long non-coding RNAs in colorectal cancer

Table 2 Relationship between exosomal long non-coding RNAs and their binding molecules in colorectal cancer

Exosomal lncRNA	Expression	Interaction gene/protein	Signaling pathway	Functions	Ref.
RPPH1	↑	TUBB3	-	Promotes metastasis and proliferation of CRC cells	Liang et al[44]
APC1	↓	Rab5b	MAPK pathway	Inhibits metastasis, and angiogenesis of CRC	Wang et al[45]
CCAL	↑	HuR	β-catenin pathway	Suppresses cell apoptosis and promotes chemoresistance of CRC cells	Deng et al[46]
ADAMTS9-AS1	↓	β-catenin	Wnt signaling pathway	Suppresses the CRC tumorigenesis	Li et al[47]
91H	↑	HNRNPK	-	Promotes migration and invasion of CRC cells	Gao et al[48]
CRNDE-h	↑	RORγt	-	Promotes Th17 cell differentiation	Sun et al[49]

LncRNA: Long non-coding RNA; CRC: Colorectal cancer; Th: T helper.