Metabolism-associated genes in occurrence and development of gastrointestinal cancer: Latest progress and future prospect

doi:10.4251/wjgo.v13.i8.758

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World Journal of Gastrointestinal Oncology

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1948-5204

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World J Gastrointest Oncol. Aug 15, 2021; 13(8): 758-771
Published online Aug 15, 2021. doi: 10.4251/wjgo.v13.i8.758

Table 1 Up-regulated metabolism-related genes in gastric cancer based on The Cancer Genome Atlas

Gene	Con mean	Treat mean	Log FC	P value	FDR
WARS	6.463316413	33.79933632	2.386648392	5.39E-08	2.60E-07
ASS1	10.23918101	42.338062	2.047854908	5.71E-06	1.81E-05
RRM2	4.193381289	13.45216754	1.681652732	7.79E-13	9.82E-12
PSAT1	4.984197042	14.58683132	1.549233513	1.15E-07	5.23E-07
TK1	9.404335583	25.94196676	1.463889934	1.90E-08	9.60E-08
TYMS	5.252256309	13.43148698	1.354609806	8.20E-15	1.85E-13
P4HA1	5.096854107	12.3340109	1.274963063	6.70E-16	3.11E-14
MIF	19.56229893	46.31616492	1.243439876	3.49E-07	1.44E-06
AHCY	14.87041149	34.97985067	1.234079561	2.23E-10	1.71E-09
SRM	15.88621779	36.86038375	1.214295404	2.56E-11	2.26E-10
PAFAH1B3	7.126421918	16.5295421	1.213796955	4.78E-11	4.04E-10
MTHFD2	5.447936287	12.51038205	1.199344112	5.74E-16	2.85E-14
PAICS	6.543206722	14.74057996	1.171723532	9.38E-17	6.98E-15
SMS	11.67400201	26.12997113	1.162406309	5.45E-15	1.35E-13
NME1	6.553254278	14.50996199	1.146760323	5.99E-13	7.81E-12
PYCR1	9.159388726	20.07643062	1.132179571	5.23E-06	1.68E-05
CAD	4.618217342	10.01148028	1.116247328	3.37E-17	3.14E-15
ODC1	14.89150939	31.71876297	1.090846515	1.34E-06	4.97E-06
ISYNA1	4.338447403	9.180413895	1.08138036	9.64E-06	2.92E-05
PLA2G7	4.093119979	8.652040283	1.079839426	4.65E-13	6.29E-12
ENTPD6	7.372506744	15.00708695	1.025416818	5.98E-10	4.20E-09
ATIC	8.653344031	17.36986424	1.005256812	1.25E-16	8.48E-15

Log FC: Log fold change; FDR: False discovery rate.

Citation: Miao YD, Mu LJ, Mi DH. Metabolism-associated genes in occurrence and development of gastrointestinal cancer: Latest progress and future prospect. World J Gastrointest Oncol 2021; 13(8): 758-771
URL: https://www.wjgnet.com/1948-5204/full/v13/i8/758.htm
DOI: https://dx.doi.org/10.4251/wjgo.v13.i8.758