Minireviews
Copyright ©The Author(s) 2021.
World J Gastrointest Oncol. Jul 15, 2021; 13(7): 673-683
Published online Jul 15, 2021. doi: 10.4251/wjgo.v13.i7.673
Figure 3
Figure 3 Whole-exon sequencing and RNA sequencing detect mutations in tumors, and then, different methods can be used to identify hepatocellular carcinoma neoantigens. (1) Human leukocyte antigen affinity prediction; (2) Coimmunoprecipitation followed by mass spectrometry; and (3) Construction of a plasmid library based on neoantigens followed by cytotoxicity tests in vitro. HLA: Human leukocyte antigen; CO-IP: Coimmunoprecipitation.