Clinical efficacy and safety of second line and salvage aflibercept for advanced colorectal cancer in Akita prefecture

Table 3 Grade 3 or worse adverse events

Adverse event	Second-line, n = 22		Salvage therapy, n = 19
Leukopenia	0	(0)	2	(11)
Neutropenia	3	(14)	2	(11)
Febrile neutropenia	1	(5)	0	(0)
Vomiting	1	(5)	0	(0)
Diarrhea	0	(0)	1	(5)
Peripheral sensory neuropathy	0	(0)	2	(11)
Hypertension	2	(9)	1	(5)
Proteinuria	1	(5)	2	(11)
Perianal abscess	1	(5)	1	(5)

Data are presented as n (%).