BRAFV600E mutant colorectal cancer cells mediate local immunosuppressive microenvironment through exosomal long noncoding RNAs

doi:10.4251/wjgo.v13.i12.2129

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Dec 15, 2021; 13(12): 2129-2148
Published online Dec 15, 2021. doi: 10.4251/wjgo.v13.i12.2129

Table 2 Relationship between BRAF^V600E mutation and microvascular density/microlymphatic vessel density in colorectal cancer

BRAF^V600E mutation	MVD		MLVD
BRAF^V600E mutation	mean ± SD	P value	mean ± SD	P value
+	38.53 ± 17.11	0.030	9.67 ± 5.63	0.0001
-	27.54 ± 9.54	0.030	3.81 ± 2.06	0.0001

MVD: Microvascular density; MLVD: Microlymphatic vessel density.

Citation: Zhi J, Jia XJ, Yan J, Wang HC, Feng B, Xing HY, Jia YT. BRAF^V600E mutant colorectal cancer cells mediate local immunosuppressive microenvironment through exosomal long noncoding RNAs. World J Gastrointest Oncol 2021; 13(12): 2129-2148
URL: https://www.wjgnet.com/1948-5204/full/v13/i12/2129.htm
DOI: https://dx.doi.org/10.4251/wjgo.v13.i12.2129