Basic Study
Copyright ©The Author(s) 2021.
World J Gastrointest Oncol. Dec 15, 2021; 13(12): 2101-2113
Published online Dec 15, 2021. doi: 10.4251/wjgo.v13.i12.2101
Table 1 hMLH1 methylation status in the Filipinos colorectal cancer patients
Normal tissue (%)
Tumor tissue(%)
Normal/tumor (%)

M
U

M
U

M/M
U/U
M/U or U/M


Freq
19
35
P value
5
49
P value
4
34
16
P value
Gender
Male309 (30)21 (70)NS2 (7)28 (93)NS11 (3)20 (67)9 (30)NS
Female2410 (42)14 (58)3 (12)21 (88)3 (13)14 (58)7 (29)
Age
≤ 4053 (60)2 (40)NS10 (0)5 (100)NS10 (0)2 (40)3 (60)NS
> 404916 (33)33 (67)5 (10)44 (90)4 (8)32 (65)13 (27)
Location of tumor
Proximal64 (67)2 (33)NS12 (33)4 (67)0.0312 (33)2 (33)2 (33)0.029
Distal/rectum4815 (31)33 (69)3 (6)45 (94)2 (4)32 (67)14 (29)
Tumor grade
Poor85 (62)3 (38)NS1 (12)7 (88)NS1 (12)3 (38)4 (50)NS
Moderate4413 (30)31 (70)4 (9)40 (91)3 (7)30 (68)11 (25)
Well21 (50)1 (50)0 (0)2 (100)0 (0)1 (50)1 (50)
Tumor stage
I-II206 (30)14 (70)NS2 (10)18 (90)NS12 (10)14 (70)4 (20)NS
III-IV3413 (38)21 (62)3 (9)31 (91)2 (6)20 (59)12 (35)