Dysbiosis of the duodenal microbiota as a diagnostic marker for pancreaticobiliary cancer

Table 7 Microbiome comparison in patients with pancreatic disease

	Benign pancreatic diseases (n = 16)	Pancreatic cancer (n = 9)	P value
Bacteroides, %, median (range)	2.1 (0-26.1)	5.8 (0-46.4)	0.17
Bifidobacterium, %, median (range)	0 (0-0.5)	0.48 (0-4.5)	0.03
Clostridium cluster IV, %, mean ± SD	4.0 ± 3.3	3.6 ± 2.9	0.76
Clostridium cluster IX, %, mean ± SD	5.3 ± 3.6	6.4 ± 5.2	0.57
Clostridium cluster XI, %, median (range)	0 (0-0)	0 (0-0)
Clostridium cluster XVIII, %, median (range)	1.4 (0-3.9)	3.0 (0.8-14.9)	0.04
Clostridium subcluster XIVa, %, median (range)	3.8 (0-21.4)	6.0 (2.9-13.7)	0.32
Lactobacillales, %, mean ± SD	68.4 ± 19.3	59.7 ± 20.4	0.3
Prevotella, %, median (range)	4.2 (2.5-20.4)	4.0 (1.5-6.3)	0.3
Others, %, median (range)	2.0 (0-18.3)	0.3 (0-11.0)	0.3