Novel perspective in pancreatic cancer therapy: Targeting ferroptosis pathway

Figure 3 Regulatory molecules of ferroptosis in pancreatic ductal adenocarcinoma. ARF6: ADP ribosylation factor 6; ATG5/7: Autophagy-related 5/7; BCAT2: Branched-chain amino acid transaminase 2; cGAS: Cyclic GMP-AMP synthase; FBW7: F-box and WD repeat domain-containing 7;IREB2: Iron-responsive element-binding protein 2; HSPA5: Heat shock 70-kDa protein 5; LTF: Lactotransferrin; MGST: Microsomal glutathione transferase 1; NCOA4: Nuclear receptor coactivator 4; NEDD4L: Neural precursor cell-expressed developmentally downregulated 4-like; NR4A1: Nuclear receptor subfamily 4 group A member 1; PIR: Pirin; RSL3: RAS-selective lethal small molecule 3; SAT1: Spermidine/spermine N1-acetyltransferase 1; SCD1: Stearoyl-CoA desaturase-1. STING1: Stimulator of interferon genes; TFAM: Transcription factor A, mitochondrial.