Extracellular vesicles: General features and usefulness in diagnosis and therapeutic management of colorectal cancer

Figure 6 Colorectal cancer cells extracellular vesicles molecules as relevant cancer biomarkers. Among all the molecules present in extracellular vesicles, only a subset (proteins, miRNAs, lncRNAs) have been shown to be of potential clinical value on colorectal cancer detection, diagnosis, prognosis and treatment response evaluation. All referenced markers were found to be differentially expressed in cancer patients and in healthy people. The yellow ones were useful for diagnosis, the green ones for progression, the blue ones for prognosis and the pink ones were associated with chemoresistance. TAM: Tumor associated macrophages.