Anatomical vs nonanatomical liver resection for solitary hepatocellular carcinoma: A systematic review and meta-analysis

Table 2 Results of meta-analysis comparison of anatomical resection and non-anatomical resection

	Studies	Patients		MD/OR (95%CI)	P value	Study heterogeneity
		AR	NAR			χ2	df	I2, %	P value
Operating time (min)	9	782	954	47.08 (26.30-67.86)	< 0.001	60.82	8	87	< 0.001
Blood loss (mL)	8	749	921	169.29 (65.88-272.70)	0.001	110.72	7	94	< 0.001
Blood transfusion	8	749	921	1.16 (0.84-1.60)	0.36	8.75	6	31	0.19
Surgical margin (mm)	6	322	494	1.35 (0.06-2.64)	0.04	7.68	5	35	0.17
Complication	5	512	684	1.24 (0.91-1.70)	0.18	4.14	4	3	0.39
1-yr OS	10	929	975	1.08 (0.69-1.68)	0.73	3.17	8	0	0.92
1-yr DFS	10	929	975	1.21 (0.85-1.72)	0.29	16.92	9	47	0.05
5-yr OS	14	4260	5184	1.19 (1.08-1.30)	< 0.001	19.04	13	32	0.12
5-yr DFS	11	3113	4542	1.26 (1.15-1.39)	< 0.001	15.76	10	37	0.11

AR: Anatomical resection; NAR: Non-anatomical resection; OS: Overall survival; DFS: Disease-free survival; MD: Mean difference; OR: Odds ratio; CI: Confidence interval; df: Degrees of freedom.