Cell-free DNA liquid biopsy for early detection of gastrointestinal cancers: A systematic review

Table 2 Number of patients in each group

Ref.	Total patients in validation cohort	Nbr patient cancer group	Nbr patient healthy group	Nbr patient additional group 1	Nbr patient in aditionnal group 2
Li et al[13]	208	101	107	-	-
Chen et al[14]	418	113	2071	98 pre-diagnosed patients	-
Guler et al[18]	228	23	205	-	-
Junca et al[12]	130	20	40	39 advance adenoma	31 non-advance adenoma
Tao et al[15]	175	89	86	-	-
Cristiano et al[19]	423	208	215	-	-
Li et al[17]	140	74	66	-	-
Qu et al[16]	331	-	-	HBsAg (+)	-
Cai et al[11]	1194	809	256	129 LC/CHB	-
Wan et al[9]	817	546	271	-	-
Jensen et al[20]	234	143	91	-	-
Nunes et al[21]	356	253	103	-	-
Perrone et al[22]	170	34	63	73 adenoma/hyperplasia	-

LC: Liver cirrhosis, CHB: Chronic hepatitis B virus infection. 90 GC patients without surgery and 110 who had undergone surgery.