Prognostic significance of Borrmann type combined with vessel invasion status in advanced gastric cancer

Table 3 Univariate and multivariate analyses of postoperative prognostic factors for advanced gastric cancer

	Univariate analysis		Multivariate analysis
	HR (95%CI)	P value	HR (95%CI)	P value
Gender	1.027 (0.925-1.139)	0.619	-	-
Age	0.983 (0.898-1.076)	0.705	-	-
Lymphatic and/or blood vessel invasion	0.733 (0.653-0.823)	< 0.001	0.869 (0.770-0.981)	< 0.001
Borrmann type	1.591 (1.481-1.710)	< 0.001	1.217 (1.130-1.312)	0.023
Tumor location	1.120 (1.061-1.183)	< 0.001	0.990 (0.940-1.043)	0.718
Tumor size (mm)	1.842 (1.667-2.036)	< 0.001	1.149 (1.031-1.280)	0.012
Histologic grade	1.248 (1.135-1.372)	< 0.001	1.021 (0.927-1.125)	0.667
pT category	1.413 (1.334-1.497)	< 0.001	1.180 (1.180-1.258)	< 0.001
pN category	1.622 (1.553-1.694)	< 0.001	1.447 (1.382-1.515)	< 0.001
Surgical approach	1.474 (1.360-1.598)	< 0.001	1.076 (0.988-1.172)	0.094
Radical surgery	2.906 (2.607-3.239)	< 0.001	2.029 (1.810-2.276)	< 0.001
Combined resection	0.641 (0.508-0.809)	< 0.001	0.859 (0.677-1.090)	0.212