Comparison of hyperthermic intraperitoneal chemotherapy regimens for treatment of peritoneal-metastasized colorectal cancer

Table 1 Patients, tumours and treatment, n (%)

	All, n = 102	MMC, n = 34	Oxaliplatin/5-FU, n = 68	P value1
Male sex	60 (59)	24 (40)	36 (60)	0.135
Age in yr, median (range)	57.2 (23-80)	56.3 (23-73)	57.7 (40-80)	0.884
BMI in kg/m²	25.3 (15.9-39.6)	25.5 (19.1-33.6)	25.2 (15.9-39.6)	0.266
ASA-score				0.002b
1-2	49 (48)	24 (71)	25 (37)
3-4	53 (52)	10 (29)	43 (63)
Tumour location				1.000
Colon	91 (89)	30 (88)	61 (90)
Rectum	11 (11)	4 (12)	7 (10)
Surgical approach				0.257
Complete cytoreduction	99 (97)	32 (94)	67 (99)
Palliative resection	3 (3)	2 (6)	1 (2)
Resection
Peritoneum	81 (80)	29 (85)	52 (77)	0.437
Omentum	66 (65)	26 (77)	40 (59)	0.123
Colon/rectum	55 (54)	18 (53)	37 (54)	1.000
Small intestine	49 (48)	15 (44)	34 (50)	0.675
Liver	42 (41)	13 (38)	29 (43)	0.831
Diaphragm	16 (16)	9 (27)	7 (10)	0.045a
Other	63 (64)	21 (68)	42 (62)	0.655
Pretherapeutic T stage				0.027a
T1	2 (2)	0	2 (3)
T2	2 (2)	0	2 (3)
T3	34 (34)	13 (41)	21 (31)
T4a	40 (40)	17 (53)	23 (34)
T4b	22 (22)	2 (6)	20 (30)
Pretherapeutic N stage				1.000
N0	26 (26)	8 (25)	18 (27)
N+	73 (74)	24 (75)	49 (73)
Pretherapeutic M stage				1.000
M0	36 (37)	12 (35)	24 (38)
M+	62 (63)	22 (65)	40 (63)
Tumour grading				1.000
G1	0	0	0
G2	59 (63)	22 (65)	37 (63)
G3	34 (37)	12 (35)	22 (37)
PCI score (0-39)	9.4 (0-39)	12.0 (0-39)	8.1 (0-30)	0.312
Postop CC-level				0.350
CC0	89 (87)	28 (82)	61 (90)
CC1	8 (8)	3 (9)	5 (7)
CC2/3	5 (5)	3 (9)	2 (3)
Mucinous cells	21 (21)	6 (18)	15 (22)	0.796

¹Fisher's exact test.

^aP < 0.05.

^bP < 0.01. 5-FU: 5-Fluorouracil; ASA: American Society of Anesthesiologists; BMI: Body mass index; MMC: Mitomycin C; PCI: Peritoneal cancer index.