Retrospective Cohort Study
Copyright ©The Author(s) 2020.
World J Gastrointest Oncol. Jul 15, 2020; 12(7): 741-755
Published online Jul 15, 2020. doi: 10.4251/wjgo.v12.i7.741
Table 2 Expression of immunohistochemical markers and frequency of TP53 gene mutations
ParameterNumber (n = 266), n (%)
Maspin expression in tumor coreNegative39 (14.66)
Cytoplasm125 (46.99)
Mixed (nucleus+cytoplasm)85 (31.96)
Nuclear17 (6.39)
Maspin expression in the invasion frontNegative21 (7.90)
Cytoplasm0 (0)
Mixed (nucleus+cytoplasm)201 (75.56)
Nuclear44 (16.54)
p53 – nuclear expressionNegative40 (15.04)
5%-50%69 (25.94)
> 50%157 (59.02)
TP53 gene statusWild-type176 (66.17)
Mutations90 (33.83)