Clinical significance of expression of fibrous sheath interacting protein 1 in colon cancer

Table 1 Correlation between fibrous sheath interacting protein 1 expression and clinicopathological features (n = 302), n (%)

Characteristic (%)	FSIP1 negative (n = 203)	FSIP1 positive (n = 99)	P value
Median age	63 ± 17.6	59 ± 20.8	0.521
Sex
Male	121 (60)	54 (55)	0.438
Female	82 (40)	45 (45)
Tumor size			0.313
< 5	85 (41)	39 (39)
5-10	97 (48)	49 (49)
> 10	21 (5)	11 (12)
Pathological tumor stage			0.0011
T1	89 (44)	30 (30)
T2	46 (23)	17 (17)
T3	44 (22)	25 (25)
T4	24 (11)	27 (28)
Pathological nodal stage			0.0001
N0	65 (32)	20 (20)
N1	78 (38)	33 (33)
N2	39 (19)	28 (28)
N3	21 (11)	18 (19)
Tumor differentiation			0.0001
Well	71 (35)	45 (46)
Moderate	85 (42)	31 (31)
Poor	47 (23)	23 (23)

¹The results were statistically significant (P < 0.01). The results showed that high expression of fibrous sheath interacting protein 1 was positively correlated with colon cancer stage and lymph node metastasis and negatively correlated with tumour differentiation. FSIP1: Fibrous sheath interacting protein 1.