Changes in extracellular matrix in different stages of colorectal cancer and their effects on proliferation of cancer cells

Figure 4 Cancer cells co-cultured with colorectal cancer extracellular matrix and normal tissue extracellular matrix in vitro. Compared to the optical density (OD) value of the normal tissue extracellular matrix (ECM), the OD value of colorectal cancer (CRC) ECM was higher. When comparing every two OD values of the CRC ECM, the difference between stage I ECM and stage II ECM was not statistically significant (P = 0.138).