Impact of preoperative chemoradiotherapy using concurrent S-1 and CPT-11 on long-term clinical outcomes in locally advanced rectal cancer

Table 1 Patient characteristics

Characteristic	n = 82
Age (yr)
Median (range)	64 (34–79)
Sex
Male	60 (73.2)
Female	22 (26.8)
Distance from anal verge (cm)
Median (range)	5.0 (0–8)
Size of tumor (cm)
Median (range)	4.5 (2–9)
Clinical T stage (before chemoradiotherapy)
3	72 (87.8)
4	10 (12.2)
Mesorectal fascia invasion
−	53 (64.6)
+	29 (35.4)
Extramural vascular invasion
−	46 (56.1)
+	36 (43.9)
Clinical N stage (before chemoradiotherapy)
−	36 (43.9)
+	46 (56.1)
Subgroup of locally advanced rectal cancer
Bad	50 (61.0)
Ugly	32 (39.0)
UGT1A1 polymorphism (in 48 patients)
Wild type	25 (52.1)
Mutant type	23 (47.9)

Data are n (%) unless otherwise shown.