Caffeine and its main targets of colorectal cancer

doi:10.4251/wjgo.v12.i2.149

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Feb 15, 2020 (publication date) through Nov 2, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Feb 15, 2020; 12(2): 149-172
Published online Feb 15, 2020. doi: 10.4251/wjgo.v12.i2.149

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Figure 8 The main targets and changes induced by caffeine acting on cytokines and their effects. Examples of mediated targets are A1R, A2R, ryanodine receptor and concanavalin A. Caffeine induces a decline in cytokines, such as tumor necrosis factor-alpha, interleukin (IL)-10, IL-4, IL-2, interferon-γ and exerts a differential effect. RyR: Ryanodine receptor; ConA: Concanavalin A; TNF-α: Tumor necrosis factor-alpha; IL: Interleukin; IFN: Interferon.

Citation: Cui WQ, Wang ST, Pan D, Chang B, Sang LX. Caffeine and its main targets of colorectal cancer. World J Gastrointest Oncol 2020; 12(2): 149-172
URL: https://www.wjgnet.com/1948-5204/full/v12/i2/149.htm
DOI: https://dx.doi.org/10.4251/wjgo.v12.i2.149