LncRNA C9orf139 can regulate the growth of pancreatic cancer by mediating the miR-663a/Sox12 axis

Figure 4 miR-663a inhibits pancreatic cancer cell growth by targeting Sox12. A: Dual-luciferase reporter assay confirmed the relationship between miR-663a and Sox12; B: Expression of Sox12 in patients with pancreatic cancer; C: Sox12 was negatively correlated with miR-663a and positively correlated with C9orf139; D: Relative expression of Sox12 mRNA and protein in cells after transfection; E: Inhibited cell proliferation in pancreatic cancer cells transfected with si-Sox12; F: Inhibited cell invasion in pancreatic cancer cells transfected with si-Sox12; G: Inhibited cell migration in pancreatic cancer cells transfected with si-Sox12; H: Increased cell apoptosis in pancreatic cancer cells transfected with si-Sox12. ^bP < 0.01 compared with the control group; ^eP < 0.001 compared with the control group.