Pathological significance of abnormal recepteur d’origine nantais and programmed death ligand 1 expression in colorectal cancer

Figure 1 X-tile analysis to determine the optimal cut-off values for RON and PD-L1 expression and survival analysis in the GEO dataset. The optimal cut-off values are highlighted by black circles (left panels) and shown in histograms for the entire cohort (middle panels). Kaplan-Meier survival plots are shown in right panels. A: The optimal cut-off value for RON was 7.50 (χ² = 4.544, P = 0.033); B: The optimal cut-off value for PD-L1 was 4.30 (χ² = 4.078, P = 0.043); C: Effect of different RON and PD-L1 expression states on patient survival. ^aP < 0.05.