Cancer-related microangiopathic hemolytic anemia in patients with advanced gastric cancer: A retrospective single-center analysis

doi:10.4251/wjgo.v12.i11.1288

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Oncol. Nov 15, 2020; 12(11): 1288-1295
Published online Nov 15, 2020. doi: 10.4251/wjgo.v12.i11.1288

Table 2 Treatment and response

Patient number	1^st chemo therapy	2^nd chemo therapy	MAHA baseline			MAHA day 14			PFS in wk	RS in wk	OS in wk
			Pts	Hb	Sch	Plt	Hb	Sch
1	FLO	FOLFIRI	8	5.9	31	84	9.6	12	9	1.1	10.3
2	No	NA	32	7.7	40	NA	NA	NA	0.1	NA	0.1
3	FLO	Paclitaxel	34	8.0	15	65	10.7	-	25.7	0.1	27.1
4	FOLFIRI-Ram¹	NA	168	5.4	40	204	11.6	-	32.1	NA	NA
5	FLOT	No	130	7.8	35	NA	NA	NA	1.0	NA	1.0
6	FLOT	FOLFIRI-Ram	44	8.4	25	208	8.8	25	25.4	2.3	28.0
7	FLOT	No	46	6.9	97	NA	NA	NA	0.3	NA	0.3
8	No	NA	36	8.2	17	NA	NA	NA	1.86	NA	1.86

¹Diagnosis of microsatellite instability-high tumor. FLO: 5-Fluorouracil (5-FU), leucovorin, oxaliplatin; FLOT: 5-FU, leucovorin, oxaliplatin, docetaxel; FOLFIRI: 5-FU, leucovorin, irinotecan; Hb: Hemoglobin (gram per deciliter); NA: Not applicable; OS: Overall survival; PFS: Progression-free survival; Plt: Platelet count (per nanoliter); RAM: Ramucirumab; RS: Residual survival; Sch: Schistocytes (per milliliter).

Citation: Berger AK, Allgäuer M, Apostolidis L, Schulze-Schleithoff AE, Merle U, Jaeger D, Haag GM. Cancer-related microangiopathic hemolytic anemia in patients with advanced gastric cancer: A retrospective single-center analysis. World J Gastrointest Oncol 2020; 12(11): 1288-1295
URL: https://www.wjgnet.com/1948-5204/full/v12/i11/1288.htm
DOI: https://dx.doi.org/10.4251/wjgo.v12.i11.1288