Comparison of prognostic factors in different age groups and prognostic significance of neutrophil-lymphocyte ratio in patients with gastric cancer

Table 7 Summary of meta-regression and the subgroup analysis

Subgroup	1P value	n	HR	95%CI	I2	2P value
Design	0.715
Retrospective		15	1.54	1.39-1.70	14.8	0.287
Prospective		4	1.61	1.31-1.98	9.1	0.345
Sample size	0.879
< 400		12	1.56	1.38-1.76	2	0.424
≥ 400		7	1.54	1.37-1.77	29.8	0.201
Cut-off value	0.223
< 3		10	1.46	1.29-1.66	33.2	0.142
≥ 3		9	1.65	1.45-1.88	0	0.798
Male/all	0.225
< 0.7		14	1.50	1.36-2.66	0	0.469
≥ 0.7		5	1.75	1.43-2.13	25.6	0.251
Treatment	0.162
Surgery		13	1.49	1.34-1.67	25.1	0.190
Chemotherapy		4	1.55	1.29-1.86	0	0.982
Multiple		2	1.95	1.46-2.60	0	0.375

¹P value of meta-regression.

²P value of subgroup analysis.