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©The Author(s) 2020.
World J Gastrointest Oncol. Jan 15, 2020; 12(1): 83-91
Published online Jan 15, 2020. doi: 10.4251/wjgo.v12.i1.83
Published online Jan 15, 2020. doi: 10.4251/wjgo.v12.i1.83
Table 3 Genomic profiling by tumor type
| Total patients profiled, n = 34 | Cholangiocarcinoma | Gallbladder carcinoma, n = 2 (6%) | |
| Extrahepatic, n = 5 (15%) | Intrahepatic, n = 27 (79%) | ||
| Mutation | n (% of profiled) | n (% of profiled) | n (% of profiled) |
| TP53 | - | 10 (37) | 2 (100) |
| IDH1 | - | 8 (30) | - |
| KRAS | 1 (20) | 6 (22) | - |
| FGFR2 | 2 (40) | 4 (15) | - |
| IDH2 | - | 2 (7) | - |
| PBRM1 | - | 2 (7) | - |
| BAP1 | - | 2 (7) | - |
| NF1 | - | 1 (4) | 1 (50) |
| ARID1A | - | 1 (4) | 1 (50) |
| CDKN2A | - | - | 1 (50) |
| MET | - | 1 (4) | - |
| CCND1 | - | 1 (4) | - |
| PBX1 | - | 1 (4) | - |
| MYC | - | 1 (4) | - |
| RB1 | - | 1 (4) | - |
| MAP3K1 | - | 1 (4) | - |
| S76 | - | 1 (4) | - |
| SPTA1 | - | 1 (4) | - |
| RET | - | 1 (4) | - |
| ALK | - | 1 (4) | - |
| ATM | - | 1 (4) | - |
| CCNE1 | - | 1 (4) | - |
| GNAS | - | 1 (4) | - |
| SMAD4 | - | 1 (4) | - |
| PIK3CA | - | 1 (4) | - |
| PIK3CB | - | 1 (4) | - |
| PTEN | - | 1 (4) | - |
| PALB2 | - | 1 (4) | - |
| ARID2 | - | 1 (4) | - |
| BRCA2 | - | 1 (4) | - |
| BRAF | - | 1 (4) | - |
| MDM2 | 1 (20) | - | - |
| FRS2 | 1 (20) | - | - |
- Citation: Mizrahi JD, Gunchick V, Mody K, Xiao L, Surapaneni P, Shroff RT, Sahai V. Multi-institutional retrospective analysis of FOLFIRI in patients with advanced biliary tract cancers. World J Gastrointest Oncol 2020; 12(1): 83-91
- URL: https://www.wjgnet.com/1948-5204/full/v12/i1/83.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v12.i1.83