MicroRNA-331 inhibits development of gastric cancer through targeting musashi1

Figure 5 Musashi1 upregulation weakened miR-331 inhibitory effect in gastric cancer. A: Musashi1 (MSI1) expression was detected in gastric cancer (GC) tissues. B: MiR-331 negatively regulated MSI1 expression in GC tissues. C and D: The mRNA and protein MSI1 expressions were detected in MKN-45 cells containing MSI1 vector and miR-331 mimic. E: Cell proliferation was identified in MKN-45 cells containing MSI1 vector and miR-331 mimic. F: Protein expressions of E-cadherin, N-cadherin and Vimentin in MKN-45 cells with MSI1 vector and miR-331 mimic (G) Cell migration and invasion were identified in MKN-45 cells containing MSI1 vector and miR-331 mimic. ^bP < 0.01.