MicroRNA-331 inhibits development of gastric cancer through targeting musashi1

Figure 2 MiR-331 inhibited gastric cancer cell viability in vitro and vivo. A: MiR-331 mRNA expressions was determined in MKN-45 cells with miR-331 mimic or inhibitor. B: Cell proliferation was regulated by miR-331 mimic or inhibitor in MKN-45 cells. C: Photographs of gastric cancer (GC) tumors in miR-NC (n = 5) or miR-331 mimics (n = 5) group. Ten mice were used for xenograft tumor formation assay. Here are five of the results. D: In nude mice with miR-NC or miR-331 mimics, GC tumor volume was measured every week. E: Ki-67-stained sections of transplanted tumors in miR-NC or miR-331 mimics group. ^aP < 0.05, ^bP < 0.01.