Premalignant lesions and gastric cancer: Current understanding

Figure 1 Complete or incomplete subtypes. A: Chronic gastritis with mucosal atrophy and lymphocytic infiltrate (asterix); B: Incomplete intestinal metaplasia resembling the colonic-type epithelium with irregular mucin droplets (arrowheads) and absence of a brush border; C: Complete intestinal metaplasia resembling the small intestinal epithelium with goblet cells alternating with eosinophilic enterocytes, brush border and Paneth cells; D: Low-grade dysplasia characterized by crowded glands with columnar cells and preserved polarity and pseudostratified nuclei; E: High-grade dysplasia with cuboidal cells, mitotic activity, prominent nucleoi, and high nuclear-cytoplasmia ratio.