Retrospective evaluation of lymphatic and blood vessel invasion and Borrmann types in advanced proximal gastric cancer

Table 1 Clinicopatholgical factors according to lymphatic vessel invasion, n (%)

Variable	n	Lymphatic vessel invasion		P value
		Absent (n = 289, 65.7%)	Present (n = 151, 34.3%)
Age (yr)	440	59.86 ± 10.4	58.55 ± 11.128	0.426
Gender				0.765
Male	333 (75.7)	220 (66.1)	113 (33.9)
Female	107 (24.3)	69 (64.5)	38 (35.5)
Tumor size (cm)				0.013
≤ 5	169 (38.5)	123 (72.8)	46 (27.2)
> 5	231 (52.5)	166 (60.4)	105 (39.6)
Macroscopic type				0.003
Borrmann I-II	58 (13.2)	49 (84.5)	9 (15.5)
Borrmann III	310 (70.4)	199 (64.2)	111 (35.8)
Borrmann IV	72 (16.4)	41 (56.9)	31 (43.1)
Adjacent organs invaded1				0.815
With	105 (23.9)	70 (66.7)	36 (33.3)
Without	335 (76.1)	219 (65.4)	116 (34.6)
Histologic grade				0.001
Well	203 (46.1)	149 (73.4)	54 (26.6)
Poor	237 (53.9)	140 (59.1)	97 (40.9)
AJCC pT category				0.002
pT2	53 (12.0)	37 (69.8)	16 (30.2)
pT3	136 (31.0)	104 (76.5)	32 (23.5)
pT4a	251 (57.0)	148 (59.0)	103 (41.0)
AJCC pN category				0.000
pN0	102 (23.2)	96 (94.1)	6 (5.9)
pN1	71 (16.2)	51 (71.8)	20 (28.2)
pN2	98 (22.2)	65 (66.3)	33 (33.7)
pN3a	89 (20.2)	47 (52.8)	42 (47.2)
pN3b	80 (18.2)	30 (37.5)	50 (62.5)
Resection type				0.426
Proximal	97 (22.1)	67 (69.1)	30 (30.1)
Total	343 (77.9)	222 (64.7)	121 (35.3)
Combined other organ resection				0.815
No	396 (90.0)	259 (65.4)	137 (34.6)
Yes	44 (10.0)	30 (68.2)	14 (31.8)
Survival at 5 yr	34.2%	42.5%	25.1%	0.000

¹Adjacent organs invaded were diagnosed by the surgeon intraoperatively.