Plasma and wound fluid levels of eight proangiogenic proteins are elevated after colorectal resection

Table 3 The fall increased in wound fluid per corresponding mean plasma levels

Analyzed protein	The fall increased in wound fluid per corresponding mean plasma levels								Increased range
	benign	cancer	benign	cancer	benign	cancer	benign	cancer	benign	cancer
	POD1	POD1	POD3	POD3	POD7-13	POD7-13	POD14-20	POD14-20
ANG-2	3.3	3.0	5.5	6.0	12.8	12.0	8.0	3.5	3-13	3-12
VEGF	15.5	19.0	22.9	36.0	59.0	61.0	60.5	106.0	16-61	19-106
MMP-2	0.96	2.0	1.8	2.0	4.5	4.0	4.5	3.3	1-5	2-4
PLGF	40.8	16.0	88.2	61.0	100.3	46.0	106.1	27.2	41-106	16-61
MMP-3	2.6	5.2	4.6	5.0	6.5	3.2	8.8	5.4	3-9	3.2-5.3
OPN	4.9	3.1	14.0	12.0	24.2	14.0	15.5	9.3	5-23	3.1-14
MCP-1	39.7	40.0	74.7	37.0	85.2	59.0	16.0	57.1	16-86	37-59
CHI3L1	0.6	0.7	6.9	3.0	5.7	9.0	3.6	5.0	1-7	3-9

ANG2: Angiopoetin-2; VEGF: Vascular endothelial growth factor; MMP2: Matrix metalloproteinase-2; PLGF: Placental growth factor; MMP3: Matrix metalloproteinase-3; OPN: Osteopontin; MCP-1: Monocyte chemotactic protein-1; CHI3L1: Chitinase 3 like protein-1; POD: Post-operative day.