Significance of HER2 protein expression and HER2 gene amplification in colorectal adenocarcinomas

Figure 3 Kaplan-Meier overall survival analysis. A: Kaplan-Meier overall survival (OS) analysis of colorectal adenocarcinoma patients based on human epidermal growth factor receptor 2 (HER2) expression status (as determined by fluorescence in situ hybridization); B: Kaplan-Meier OS analysis of tubular adenocarcinoma patients age ≤ 65 based on HER2 expression status; C: Kaplan-Meier OS analysis of tubular adenocarcinoma patients with moderate-poor differentiation and age ≤ 65 based on HER2 expression status; D: Kaplan-Meier overall survival analysis of tubular adenocarcinoma patients with stage T2-4 tumors and age ≤ 65 based on HER2 expression status. HER2: Human epidermal growth factor receptor 2; FISH: Fluorescence in situ hybridization.