Copyright
©The Author(s) 2019.
World J Gastrointest Oncol. Apr 15, 2019; 11(4): 335-347
Published online Apr 15, 2019. doi: 10.4251/wjgo.v11.i4.335
Published online Apr 15, 2019. doi: 10.4251/wjgo.v11.i4.335
Table 5 Overall survival based on clinicopathological features
Clinicopathological features | Patients | Events | Median survival (95%CI), mo | P-value |
Gender | 0.707 | |||
Male | 640 | 144 | NA | |
Female | 418 | 100 | NA | |
Age (yr) | ||||
≤ 60 | 522 | 116 | NA | 0.591 |
> 60 | 536 | 128 | NA | |
≤ 65 | 661 | 138 | NA | 0.027 |
> 65 | 397 | 106 | NA | |
Tumor site | 0.457 | |||
Colon | 568 | 133 | NA | |
Rectal | 490 | 111 | NA | |
Tumor grade | 0.000 | |||
1-2 | 839 | 176 | NA | |
3 | 219 | 68 | NA | |
Histology | 0.000 | |||
Tubular | 971 | 205 | NA | |
Mucinous/ Other types | 87 | 39 | 54.90 | |
Lymph node metastasis | 0.000 | |||
No | 562 | 61 | NA | |
Yes | 496 | 183 | NA | |
Tumor stage | 0.000 | |||
I-II | 198 | 13 | NA | |
III-IV | 860 | 231 | NA | |
HER2 protein overexpression by IHC | ||||
IHC (-) | 935 | 221 | NA | 0.220 |
IHC (+) | 123 | 23 | NA | |
HER2 gene amplification by FISH | ||||
Positive | 1022 | 234 | NA | 0.458 |
Negative | 36 | 10 | NA |
- Citation: Wang XY, Zheng ZX, Sun Y, Bai YH, Shi YF, Zhou LX, Yao YF, Wu AW, Cao DF. Significance of HER2 protein expression and HER2 gene amplification in colorectal adenocarcinomas. World J Gastrointest Oncol 2019; 11(4): 335-347
- URL: https://www.wjgnet.com/1948-5204/full/v11/i4/335.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v11.i4.335