Predictive factors of histological response of colorectal liver metastases after neoadjuvant chemotherapy

Table 5 Prognostic factors of overall survival

No vascular neoplastic microemboli on histology
	Hazard ratio	95%CI	P-value
Responder
NR	1	[0.35; 0.86]	0.010
R	0.55
Gender
F	1	[1.11; 2.58]	0.014
M	1.70
Targeted preoperative therapy
No	1	[1.40; 3.62]	0.001
Yes	2.25
Two-stage procedure
No	1	[1.18; 3.06]	0.008
Yes	1.90
N+ status of the primary tumor
No	1	[1.10; 2.84]	0.018
Yes	1.77
Presence of vascular neoplastic microemboli on histology
	Hazard ratio	95%CI	P-value
Gender
F	1	[1.11; 2.58]	0.014
M	1.70
Targeted preoperative therapy
No	1	[1.40; 3.62]	0.001
Yes	2.25
Two-stage procedure
No	1	[1.18; 3.06]	0.008
Yes	1.90
N+ status of the primary tumor
No	1	[1.10; 2.84]	0.018
Yes	1.77

NR: Non-responders; R: responders; F: Female; M: Male.