C-reactive protein may be a prognostic factor for the whole gastroenteropancreatic neuroendocrine tumor group

Table 2 Relationship between categorical independent variables and survival

		Mean survival (mo)	Standard deviation (± mo)	1-yr survival (%)	3-yr survival (%)	5-yr survival (%)	P value
All patients	n = 93	102.5	6.3	90	72	61
Non-surgical (non-invasive) group	Yes (n = 56)	101.9	7.3	91	75	66	0.25
	No (n = 37)	93.2	10.3	89	67	54
Surgical resection	Yes (n = 54)	99.6	8.4	89	70	59	0.62
	No (n = 39)	97	8.5	92	74	64
Liver metastasis	Present (n = 38)	61.3	9.5	81	47	29	< 0.001
	Absent (n = 55)	122.6	5.5	96	89	83
Extrahepatic metastasis	Present (n = 23)	32	5.8	78	30	08	< 0.001
	Absent (n = 70)	124	6	94	85	78
Stage	1 (n = 35)	132.8	4.3	100	94	91	< 0.001
	2 (n = 7)			100	100	100
	3 (n = 13)	69.7	8.5	84	70	54
	4 (n = 38)			81	47	29
Grade mitotic count	1 (n = 62)	111	6.2	97	84	72	< 0.001
	2 (n = 21)	87.1	14.4	81	57	52
	3 (n = 10)	35.1	11.3	70	30	10
Grade Ki-67 level	1 (n = 43)	124.6	6.1	97	90	86	< 0.001
	2 (n = 30)	83.9	9.9	90	66	50
	3 (n = 20)	54.4	12.7	75	40	25
Anemia	Present (n = 42)	92.9	8.7	90	71	57	0.34
	Absent (n = 47)	110	8.6	90	76	68
Hypoalbuminemia	Present (n = 10)	91	15.7	100	70	60	0.60
	Absent (n = 77)	105.4	6.8	89	75	63
ESR elevation	Present (n = 30)	93.5	9.5	93	76	60	0.28
	Absent (n = 33)	117.7	9.2	93	81	72
CRP elevation (mg/L)	< 5 (n = 28)	118.1	8.2	100	85	78	0.009
	5-20 (n = 20)	118.6	12.2	90	80	75
	> 20 (n = 24)	72.3	10.5	83	66	41

CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate.