Relationship between cachexia and perineural invasion in pancreatic adenocarcinoma

doi:10.4251/wjgo.v11.i12.1126

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World Journal of Gastrointestinal Oncology

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1948-5204

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World J Gastrointest Oncol. Dec 15, 2019; 11(12): 1126-1140
Published online Dec 15, 2019. doi: 10.4251/wjgo.v11.i12.1126

Table 1 Patient characteristics in the adenocarcinoma and control groups, n (%)

Characteristics	PDAC (n = 114)	Control (n = 125)
Age (yr), mean (SD)	64.76 (10.58)^b	60.26 (12.03)
Age > 50 yr	103 (90.35)^b	89 (71.2)
Sex (female)	47 (41.23)	46 (36.8)
BMI (kg/m²), median (IQR)	25.09 (22.05-27.25)	25.26 (22.58-28.72)
Weight status
Underweight	12 (10.53)	5 (4)
Normal	48 (42.11)	53 (42.4)
Overweight	37 (32.46)	44 (35.2)
Obesity	17 (14.91)	23 (18.4)
Smoking	50 (43.86)	69 (55.2)
New-onset diabetes	24 (21.05)^b	8 (6.4)
Long-term diabetes	24 (21.05)	32 (25.6)
Diabetes	49 (42.98)^a	38 (30.4)
CA 19-9 (U/mL), median (IQR)	400 (67.75-400)^b	31.45 (9.58-98.8)
Cachexia	22 (19)	8 (6)
T stage	1-2: 10 (8.85); 3: 65 (57.52); 4: 38 (33.63)
Histological grade	G1: 8/41 (19.51); G2: 24/41 (58.54); G3: 12/41 (29.27)
N stage	9 (8.18)
Metastasis	48 (42.11)

^aP < 0.05,

^bP < 0.01 vs controls. PDAC: Pancreatic ductal adenocarcinoma; BMI: Body-mass index; CA 19-9: Carbohydrate antigen 19-9; QR: Interquartile range; CI: Confidence interval.

Citation: Petrusel L, Rusu I, Leucuta DC, Seicean R, Suharoschi R, Zamfir P, Seicean A. Relationship between cachexia and perineural invasion in pancreatic adenocarcinoma. World J Gastrointest Oncol 2019; 11(12): 1126-1140
URL: https://www.wjgnet.com/1948-5204/full/v11/i12/1126.htm
DOI: https://dx.doi.org/10.4251/wjgo.v11.i12.1126