Copyright
©The Author(s) 2019.
World J Gastrointest Oncol. Nov 15, 2019; 11(11): 998-1010
Published online Nov 15, 2019. doi: 10.4251/wjgo.v11.i11.998
Published online Nov 15, 2019. doi: 10.4251/wjgo.v11.i11.998
Table 4 Combined effect of TLR9-1237 T/C and TLR9-1486 C/T polymorphisms on risk of GC and CG
| Risk genotype | Groups | OR (95%CI), P value | |||||
| TLR9-1237 | TLR9-1486 | C, n = 200 | GC, n = 161 | CG, n = 248 | GC × C | CG × C | GC × CG |
| TT | CC | 50 | 7 | 38 | 1.00 | 1.00 | 1.00 |
| TC/CC | CC | 5 | 13 | 7 | 18.57 (5.06-68.15), < 0.0001 | 1.842 (0.54-6.25), 0.3665 | 10.08 (2.96-34.24). 0.0002 |
| TT | CT/TT | 98 | 70 | 150 | 5.102 (2.18-11.92), < 0.0001 | 7.737(4.72-12.66), < 0.0001 | 2.533 (1.07-5.95), 0.0307 |
| TC/CC | CT/TT | 47 | 71 | 53 | 10.79 (4.50-25.83), < 0.0001 | 1.484 (0.83-1.64), 0.1911 | 7.272 (3.01-17.56), < 0.0001 |
- Citation: Susi MD, Lourenço Caroline M, Rasmussen LT, Payão SLM, Rossi AFT, Silva AE, Oliveira-Cucolo JG. Toll-like receptor 9 polymorphisms and Helicobacter pylori influence gene expression and risk of gastric carcinogenesis in the Brazilian population.. World J Gastrointest Oncol 2019; 11(11): 998-1010
- URL: https://www.wjgnet.com/1948-5204/full/v11/i11/998.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v11.i11.998