Observational Study
Copyright ©The Author(s) 2019.
World J Gastrointest Oncol. Nov 15, 2019; 11(11): 1065-1080
Published online Nov 15, 2019. doi: 10.4251/wjgo.v11.i11.1065
Table 2 Relationship between clinicopathological features and MutL homolog1/MutS homolog2 expression in 681 patients, n (%)
ObservationPositiveaNegativebTotalχ2P value
Gender
Male310 (80.10)77 (19.90)3870.2520.625
Female240 (81.63)54 (18.37)294
Age (yr)
≤5063 (88.73)8 (11.27)713.2400.072
>50487 (79.84)123 (20.16)610
Location in the colon
Left138 (82.14)30 (17.86)1684.7460.029
Right119 (72.12)46 (27.88)165
Location of tumor Colon257 (77.18)76 (22.82)3335.3950.025
Rectum293 (84.20)55 (15.80)348
Grade of differentiation
Poor28 (66.67)14 (33.33)425.7250.017
Well-moderate522 (81.69)117 (18.31)639
Tumor stage (TNM)
II324 (82.03)71 (17.97)3950.9640.327
III226 (79.02)60 (20.98)286
Tumor size (cm)
≤4210 (78.95)56 (21.05)2660.9270. 370
>4340 (81.93)75 (18.07)415
Lymphocytic infiltration
None or little336 (82.76)70 (17.24)4061.1950.332
Marked or moderate214 (75.76)61 (27.24)275
Mucin
Positive108 (73.97)38 (26.03)1465.5170.024
Negative442 (82.62)93 (17.38)535
Circumscribed margin
Negative482 (79.80)122 (20.20)6043.1840.090
Positive68 (88.31)9 (11.69)77