Copyright
©The Author(s) 2019.
World J Gastrointest Oncol. Nov 15, 2019; 11(11): 1011-1020
Published online Nov 15, 2019. doi: 10.4251/wjgo.v11.i11.1011
Published online Nov 15, 2019. doi: 10.4251/wjgo.v11.i11.1011
Table 2 20-point data set observation of the study cohorts, n (%)
| Early-onset CRC | Later-onset CRC | Control | |
| N | 5710 | 63010 | 11800420 |
| Gender | |||
| Male | 2800 (49) | 32320 (51) | 4931130 (42) |
| Female | 2910 (51) | 30690 (49) | 6869290 (58) |
| Ethnicity | |||
| Caucasian | 3880 (68) | 52330 (83) | 6947160 (59) |
| African-American | 860 (15) | 8260 (13) | 1462790 (12) |
| Asian | 110 (2) | 1380 (2) | 258990 (2) |
| Symptoms | |||
| Abdominal pain | 3060 (54) | 24490 (39) | 2317490 (20) |
| Rectal pain | 170 (3) | 1260 (2) | 48200 (0.4) |
| Altered bowel function | 1440 (25) | 14610 (23) | 680420 (6) |
| Rectal bleeding | 790 (14) | 7960 (13) | 190310 (2) |
| Weight loss | 490 (9) | 7800 (12) | 147250 (1) |
| Family history | |||
| Of cancer | 1360 (24) | 9400 (15) | 308120 (3) |
| Of GI malignancy | 840 (15) | 4300 (7) | 70560 (1) |
| Of polyps | 60 (1) | 470 (1) | 15350 (0.1) |
| Social history | |||
| Tobacco use | 3600 (63) | 42360 (67) | 4838172 (41) |
| Alcohol use | 2000 (35) | 24850 (39) | 2832100 (24) |
| Comorbidities | |||
| Colitis | 710 (12) | 7270 (12) | 395260 (3) |
| BMI ≥ 30 | 3510 (61) | 36770 (58) | 4202120 (35) |
| Hypertension | 1710 (30) | 41740 (66) | 1534060 (13) |
| Hyperlipidemia | 1090 (19) | 33960 (54) | 1062040 (9) |
| Polyp history | 630 (11) | 8970 (14) | 155640 (1) |
- Citation: Syed AR, Thakkar P, Horne ZD, Abdul-Baki H, Kochhar G, Farah K, Thakkar S. Old vs new: Risk factors predicting early onset colorectal cancer. World J Gastrointest Oncol 2019; 11(11): 1011-1020
- URL: https://www.wjgnet.com/1948-5204/full/v11/i11/1011.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v11.i11.1011