MicroRNA-320a suppresses tumor progression by targeting PBX3 in gastric cancer and is downregulated by DNA methylation

Figure 3 Overexpression of miR-320a suppressed gastric cancer cell migration and invasion. A, B: Wound scratch assay was used to assess migration of MKN-45 cells. Wound healing percentage was measured at 0, 24 and 48 h after transfection with miR-320a mimics (50 nmol/L), scramble mimics, miR-320a inhibitor (100 nmol/L), scramble inhibitor or no transfection; C, D: Transwell invasion assay was carried out to determine gastric cancer cell invasion after transfection with miR-320a mimics/inhibitor, scramble mimics/inhibitor or no transfection for 48 h. Cell invasion was assessed at 24 h. ^aP < 0.05, ^bP < 0.01.