Copyright
©The Author(s) 2019.
World J Gastrointest Oncol. Oct 15, 2019; 11(10): 857-865
Published online Oct 15, 2019. doi: 10.4251/wjgo.v11.i10.857
Published online Oct 15, 2019. doi: 10.4251/wjgo.v11.i10.857
Characteristic | TNT, n = 254 (%) | Conventional neoadjuvant treatment, n = 8812 (%) | OR | 95%CI | P value |
Sex | |||||
Male | 151 (59) | 5497 (62) | 1 | Ref | |
Female | 103 (41) | 3315 (38) | 1.13 | 0.88-1.46 | 0.34 |
Race | |||||
White | 205 (81) | 7757 (88) | 1 | Ref | |
African American | 22 (8) | 624 (7) | 1.33 | 0.85-2.09 | 0.21 |
Other | 27 (11) | 431 (5) | 2.37 | 1.57-3.58 | < 0.0001 |
Comorbidity score | |||||
0 | 224 (88) | 7175 (81) | 1 | Ref | |
1 | 27 (11) | 1366 (16) | 0.63 | 0.42-0.95 | 0.026 |
≥ 2 | 3 (1) | 271 (3) | 0.35 | 0.11-1.11 | 0.08 |
Insurance | |||||
Not Insured | 9 (3) | 417 (5) | 1 | Ref | |
Private Payer | 178 (70) | 5313 (60) | 1.55 | 0.79-3.05 | 0.20 |
Government | 63 (25) | 2981 (34) | 0.98 | 0.48-1.98 | 0.95 |
Unrecorded | 4 (2) | 101 (1) | 1.84 | 0.55-6.08 | 0.32 |
Education % | |||||
≥ 29 | 39 (15) | 1262 (14) | 1 | Ref | |
20 to 28.9 | 53 (21) | 2231 (25) | 0.77 | 0.51-1.17 | 0.22 |
14 to 19.9 | 84 (33) | 2960 (34) | 0.92 | 0.62-1.35 | 0.66 |
Locations | |||||
Metro | 209 (82) | 6915 (78) | 1 | Ref | |
Urban | 16 (6) | 1474 (17) | 0.36 | 0.22-0.60 | 0.0001 |
Rural | 4 (2) | 207 (2) | 0.64 | 0.24-1.74 | 0.38 |
Unrecorded | 25 (10) | 216 (2) | 3.83 | 2.48-5.92 | < 0.0001 |
Income, United States dollars | |||||
< 30000 | 25 (10) | 1391 (16) | 1 | Ref | |
30000 to 35000 | 37 (15) | 2086 (24) | 0.99 | 0.59-1.65 | 0.96 |
35000 to 45999 | 53 (20) | 2510 (29) | 1.17 | 0.73-1.90 | 0.51 |
> 46000 | 139 (55) | 2773 (31) | 2.79 | 1.81-4.29 | < 0.0001 |
Distance to treatment facility, miles | |||||
≤ 8.5 | 82 (32) | 3561 (41) | 1 | Ref | |
> 8.5 | 172 (68) | 5205 (59) | 1.44 | 1.10-1.87 | 0.0079 |
Age distribution in yr | |||||
≤ 65 | 208 (82) | 6734 (76) | 1 | Ref | |
> 65 | 46 (18) | 2078 (24) | 0.72 | 0.52-0.99 | 0.04 |
Year of diagnosis | |||||
2004-2006 | 11 (4) | 1125 (13) | 1 | Ref | |
2007-2009 | 19 (7) | 2256 (26) | 0.86 | 0.41-1.82 | 0.69 |
2010-2012 | 73 (29) | 3097 (35) | 2.41 | 1.27-4.56 | 0.0068 |
2013-2015 | 151 (59) | 2334 (26) | 6.62 | 3.57-12.25 | <0.0001 |
Stage grouping | |||||
2 | 50 (20) | 3644 (41) | 1 | Ref | |
3 | 204 (80) | 5168 (59) | 2.88 | 2.11-3.93 | < 0.0001 |
Nodes | |||||
0 | 170 (67) | 5277 (60) | 1 | Ref | |
1 | 25 (10) | 1089 (12) | 0.71 | 0.47-1.09 | 0.12 |
- Citation: Babar L, Bakalov V, Abel S, Ashraf O, Finley GG, Raj MS, Lundeen K, Monga DK, Kirichenko AV, Wegner RE. Retrospective review of total neoadjuvant therapy. World J Gastrointest Oncol 2019; 11(10): 857-865
- URL: https://www.wjgnet.com/1948-5204/full/v11/i10/857.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v11.i10.857