Unnecessity of lymph node regression evaluation for predicting gastric adenocarcinoma outcome after neoadjuvant chemotherapy

Table 4 Comparison of overall survival among groups created based on regression change and residual tumor in lymph nodes

Groups based on regression change in LNs	Kaplan-Meier analysis		Univariate Cox proportional hazards analysis
	5-year OS rate, %	P value1	HR	95% CI	P value
A	67.5	< 0.01	0.276	0.103-0.739	0.01
B	67.4		0.356	0.133-0.955	0.04
C	28.2		1.506	0.890-2.548	0.127
D	39.5		1

¹Groups A + B vs Groups C + D. A: True negative lymph nodes (LNs) with no evidence of a preoperative therapy effect; B: No residual metastasis but presence of regression change in LNs; C: Residual metastasis with regression change in LNs; D: Metastasis with minimal or no regression change in LNs; OS: Overall survival; LNs: Lymph nodes; HR: Hazard ratio.