Copyright
©The Author(s) 2019.
World J Gastrointest Oncol. Jan 15, 2019; 11(1): 48-58
Published online Jan 15, 2019. doi: 10.4251/wjgo.v11.i1.48
Published online Jan 15, 2019. doi: 10.4251/wjgo.v11.i1.48
Characteristics | n (%) | Lymph node regression groups | P value | |||
A, n (%) | B, n (%) | C, n (%) | D, n (%) | |||
Total | 192 | 30 | 24 | 98 | 40 | |
Gender | 0.162 | |||||
Male | 139 (72.4) | 26 (86.7) | 18 (75) | 70 (71.4) | 25 (62.5) | |
Female | 53 (27.6) | 4 (13.3) | 6 (25) | 28 (28.6) | 15 (37.5) | |
Age, yr | 0.869 | |||||
< 55 | 89 (46.4) | 12 (40) | 11 (45.8) | 46 (46.9) | 20 (50) | |
≥ 55 | 103 (53.6) | 18 (60) | 13 (54.2) | 52 (53.1) | 20 (50) | |
Location | 0.876 | |||||
Esophagogastric junction | 44 (22.9) | 6 (20) | 5 (20.8) | 23 (23.5) | 10 (25) | |
Proximal gastric | 71 (37) | 13 (43.3) | 9 (37.5) | 32 (32.7) | 17 (42.5) | |
Distal gastric | 77 (40.1) | 11 (36.7) | 10 (41.7) | 43 (43.9) | 13 (32.5) | |
Maximal diameter of tumor bed | 0.259 | |||||
< 4.5 cm | 108 (56.2) | 22 (73.3) | 15 (62.5) | 50 (51) | 21 (52.5) | |
4.5-8 cm | 64 (33.3) | 8 (26.7) | 7 (29.2) | 34 (34.7) | 15 (37.5) | |
> 8 cm | 20 (10.4) | 0 (0) | 2 (8.3) | 14 (14.3) | 4 (10) | |
Histological differentiation | 0.044 | |||||
Well-moderately differentiated | 45 (23.4) | 12 (40) | 8 (33.3) | 18 (18.4) | 7 (17.5) | |
Poorly differentiated | 147 (76.6) | 18 (60) | 16 (66.7) | 80 (81.6) | 33 (82.5) | |
Laurén classification | 0.336 | |||||
Intestinal | 77 (40.1) | 17 (56.7) | 11 (45.8) | 37 (37.8) | 12 (30) | |
Diffuse | 73 (38) | 8 (26.7) | 10 (41.7) | 37 (37.8) | 18 (45) | |
Mixed | 42 (21.9) | 5 (16.7) | 3 (12.5) | 24 (24.5) | 10 (25) | |
LVI | < 0.001 | |||||
Negative | 94 (49) | 21 (70) | 20 (83.3) | 37 (37.8) | 16 (40) | |
Positive | 98 (51) | 9 (30) | 4 (16.7) | 61 (62.2) | 24 (60) | |
PNI | < 0.001 | |||||
Negative | 76 (39.6) | 17 (56.7) | 20 (83.3) | 32 (32.7) | 7 (17.5) | |
Positive | 116 (60.4) | 13 (43.3) | 4 (16.7) | 66 (67.3) | 33 (82.5) | |
AJCC ypT category | < 0.001 | |||||
0 | 11 (5.7) | 3 (10) | 6 (25) | 2 (2) | 0 (0) | |
1 | 20 (10.4) | 5 (16.7) | 6 (25) | 6 (6.1) | 3 (7.5) | |
2 | 23 (12) | 5 (16.7) | 5 (20.8) | 10 (10.2) | 3 (7.5) | |
3 | 57 (29.7) | 13 (43.3) | 4 (16.7) | 32 (32.7) | 8 (20) | |
4 | 81 (42.2) | 4 (13.3) | 3 (12.5) | 48 (49) | 26 (65) | |
AJCC ypN category | < 0.001 | |||||
0 | 54 (28.1) | 30 (100) | 24 (100) | 0 (0) | 0 (0) | |
1 | 35 (18.2) | 0 (0) | 0 (0) | 25 (25.5) | 10 (25) | |
2 | 52 (27.1) | 0 (0) | 0 (0) | 40 (40.8) | 12 (30) | |
3 | 51 (26.6) | 0 (0) | 0 (0) | 33 (33.7) | 18 (45) | |
AJCC ypTNM stage | < 0.001 | |||||
0 | 9 (4.7) | 3 (10) | 6 (25) | 0 (0) | 0 (0) | |
1 | 24 (12.5) | 9 (0) | 11 (58.3) | 4 (29.2) | 0 (0) | |
2 | 53 (27.6) | 18 (60) | 6 (25) | 20 (20.4) | 9 (22.5) | |
3 | 106 (55.2) | 0 (0) | 1 (4.2) | 74 (75.5) | 31 (77.5) | |
R0 resection | 0.029 | |||||
Yes | 159 (82.8) | 28 (93.3) | 23 (95.8) | 74 (75.5) | 34 (85) | |
No | 33 (17.2) | 2 (6.7) | 1 (4.2) | 24 (24.5) | 6 (15) | |
Mandard-TRG | < 0.001 | |||||
1 | 11 (5.7) | 3 (10) | 6 (25) | 2 (2) | 0 (0) | |
2 | 23 (12) | 7 (23.3) | 5 (20.8) | 11 (11.2) | 0 (0) | |
3 | 40 (20.8) | 8 (26.7) | 9 (37.5) | 21 (21.4) | 2 (5) | |
4 | 78 (40.6) | 6 (20) | 4 (16.7) | 47 (48) | 21 (52.5) | |
5 | 40 (20.8) | 6 (20) | 0 (0) | 17 (17.3) | 17 (42.5) |
- Citation: Zhu YL, Sun YK, Xue XM, Yue JY, Yang L, Xue LY. Unnecessity of lymph node regression evaluation for predicting gastric adenocarcinoma outcome after neoadjuvant chemotherapy. World J Gastrointest Oncol 2019; 11(1): 48-58
- URL: https://www.wjgnet.com/1948-5204/full/v11/i1/48.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v11.i1.48