Retrospective Study
Copyright ©The Author(s) 2019.
World J Gastrointest Oncol. Jan 15, 2019; 11(1): 48-58
Published online Jan 15, 2019. doi: 10.4251/wjgo.v11.i1.48
Table 2 Relationship between regression changes and residual tumor groups in lymph nodes and clinicopathological characteristics
Characteristicsn (%)Lymph node regression groups
P value
A, n (%)B, n (%)C, n (%)D, n (%)
Total19230249840
Gender0.162
Male139 (72.4)26 (86.7)18 (75)70 (71.4)25 (62.5)
Female53 (27.6)4 (13.3)6 (25)28 (28.6)15 (37.5)
Age, yr0.869
< 5589 (46.4)12 (40)11 (45.8)46 (46.9)20 (50)
≥ 55103 (53.6)18 (60)13 (54.2)52 (53.1)20 (50)
Location0.876
Esophagogastric junction44 (22.9)6 (20)5 (20.8)23 (23.5)10 (25)
Proximal gastric71 (37)13 (43.3)9 (37.5)32 (32.7)17 (42.5)
Distal gastric77 (40.1)11 (36.7)10 (41.7)43 (43.9)13 (32.5)
Maximal diameter of tumor bed0.259
< 4.5 cm108 (56.2)22 (73.3)15 (62.5)50 (51)21 (52.5)
4.5-8 cm64 (33.3)8 (26.7)7 (29.2)34 (34.7)15 (37.5)
> 8 cm20 (10.4)0 (0)2 (8.3)14 (14.3)4 (10)
Histological differentiation0.044
Well-moderately differentiated45 (23.4)12 (40)8 (33.3)18 (18.4)7 (17.5)
Poorly differentiated147 (76.6)18 (60)16 (66.7)80 (81.6)33 (82.5)
Laurén classification0.336
Intestinal77 (40.1)17 (56.7)11 (45.8)37 (37.8)12 (30)
Diffuse73 (38)8 (26.7)10 (41.7)37 (37.8)18 (45)
Mixed42 (21.9)5 (16.7)3 (12.5)24 (24.5)10 (25)
LVI< 0.001
Negative94 (49)21 (70)20 (83.3)37 (37.8)16 (40)
Positive98 (51)9 (30)4 (16.7)61 (62.2)24 (60)
PNI< 0.001
Negative76 (39.6)17 (56.7)20 (83.3)32 (32.7)7 (17.5)
Positive116 (60.4)13 (43.3)4 (16.7)66 (67.3)33 (82.5)
AJCC ypT category< 0.001
011 (5.7)3 (10)6 (25)2 (2)0 (0)
120 (10.4)5 (16.7)6 (25)6 (6.1)3 (7.5)
223 (12)5 (16.7)5 (20.8)10 (10.2)3 (7.5)
357 (29.7)13 (43.3)4 (16.7)32 (32.7)8 (20)
481 (42.2)4 (13.3)3 (12.5)48 (49)26 (65)
AJCC ypN category< 0.001
054 (28.1)30 (100)24 (100)0 (0)0 (0)
135 (18.2)0 (0)0 (0)25 (25.5)10 (25)
252 (27.1)0 (0)0 (0)40 (40.8)12 (30)
351 (26.6)0 (0)0 (0)33 (33.7)18 (45)
AJCC ypTNM stage< 0.001
09 (4.7)3 (10)6 (25)0 (0)0 (0)
124 (12.5)9 (0)11 (58.3)4 (29.2)0 (0)
253 (27.6)18 (60)6 (25)20 (20.4)9 (22.5)
3106 (55.2)0 (0)1 (4.2)74 (75.5)31 (77.5)
R0 resection0.029
Yes159 (82.8)28 (93.3)23 (95.8)74 (75.5)34 (85)
No33 (17.2)2 (6.7)1 (4.2)24 (24.5)6 (15)
Mandard-TRG< 0.001
111 (5.7)3 (10)6 (25)2 (2)0 (0)
223 (12)7 (23.3)5 (20.8)11 (11.2)0 (0)
340 (20.8)8 (26.7)9 (37.5)21 (21.4)2 (5)
478 (40.6)6 (20)4 (16.7)47 (48)21 (52.5)
540 (20.8)6 (20)0 (0)17 (17.3)17 (42.5)