HER2 inhibition in gastro-oesophageal cancer: A review drawing on lessons learned from breast cancer

doi:10.4251/wjgo.v10.i7.159

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jul 15, 2018; 10(7): 159-171
Published online Jul 15, 2018. doi: 10.4251/wjgo.v10.i7.159

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Figure 1 Simplified diagram showing signalling pathways related to human epidermal growth factor receptor 2 in gastric adenocarcinoma. VEGFR: Vascular endothelial growth factor receptor; FGFR: Fibroblast growth factor receptor; PKC: Protein kinase C; FAK: Focal adhesion kinase; HER2: Human epidermal growth factor receptor 2; MAPK: Mitogen-activated protein kinase; mTOR: Mammalian target of rapamycin.

Citation: Lote H, Valeri N, Chau I. HER2 inhibition in gastro-oesophageal cancer: A review drawing on lessons learned from breast cancer. World J Gastrointest Oncol 2018; 10(7): 159-171
URL: https://www.wjgnet.com/1948-5204/full/v10/i7/159.htm
DOI: https://dx.doi.org/10.4251/wjgo.v10.i7.159