Advances in molecular, genetic and immune signatures of gastric cancer: Are we ready to apply them in our patients’ decision making?

doi:10.4251/wjgo.v10.i7.172

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jul 15, 2018; 10(7): 172-183
Published online Jul 15, 2018. doi: 10.4251/wjgo.v10.i7.172

Table 1 Molecular subtypes of gastric cancer according to the Cancer Genome Atlas and Asian Cancer Research Group

Molecular subtypes of gastric cancer
TCGA	ACRG

CIN (50%)	MSS/TP53− (35.7%)
MSI-Η (21%)	MSS/TP53+ (26.3%)
GS (20%)	MSI-H (22.7%)
EBV + (9%)	MSS-EMT (15.3%)

TCGA: Cancer Genome Atlas; ACRG: Asian Cancer Research Group; CIN: Chrosomal instability; MSI-Η: Microsatellite-high; GS: Genomically stable; EBV: Epstein-Barr virus; MSS: Microsatellite stable; TP53: Tumor protein p53; EMT: Epithelial-mesenchymal transition.

Citation: Gkolfinopoulos S, Papamichael D, Papadimitriou K, Papanastasopoulos P, Vassiliou V, Kountourakis P. Advances in molecular, genetic and immune signatures of gastric cancer: Are we ready to apply them in our patients’ decision making? World J Gastrointest Oncol 2018; 10(7): 172-183
URL: https://www.wjgnet.com/1948-5204/full/v10/i7/172.htm
DOI: https://dx.doi.org/10.4251/wjgo.v10.i7.172