Effect of primary tumor side on survival outcomes in metastatic colorectal cancer patients after hepatic arterial infusion chemotherapy

Table 3 Univariate analysis of predictive factor of survival after first hepatic arterial infusion chemotherapy

Variable	MST (mo)	Univariate analysis		P-value
		HR	95%CI
Primary tumor site (right/left)	9.3 vs 16.3	1.353	0.881-2.079	0.167
Age (> 60/< 60 yr)	16 vs 15.5	1.026	0.731-1.440	0.88
Gender (male/female)	16.5 vs 13	0.744	0.520-1.063	0.104
Histology (poor/well to moderate)	10.3 vs 15.9	1.706	1.003-2.904	0.049*
Serum CA19-9 (≥ 37U/mL/< 37 U/mL)#	12.5 vs 21.2	2.108	1.444-3.076	< 0.001*
Serum CA72-4 (≥ 6.7 U/mL/< 6.7 U/mL)#	13 vs 20.8	1.605	1.114-2.311	0.011*
Serum CEA (≥ 5U/mL/< 5 U/mL)#	14.6 vs 21.1	1.428	0.867-2.351	0.162
Extrahepatic metastasis (present/absent)	15.8 vs 15.8	1.172	0.825-1.667	0.376
Time to liver metastasis (synchronous/ metachronous)	14.8 vs 16.5	1.125	0.802-1.580	0.495
Other local treatment (combined/uncombined)	21.1 vs 14.6	0.651	0.426-0.995	0.047*
Response to HAIC				< 0.001*
PR	21.9	0.234	0.146-0.375	< 0.001*
SD	16.1	0.285	0.185-0.439	< 0.001*
PD	7.5	1	1	NA
Infusion agents (OXA/CPT-11)	15.8 vs 22.8	1.225	0.660-2.273	0.52
Please define what this symbol represents in the table legend below
Please define what this symbol represents in the table legend below

MST: Median survival time; HR: Hazard ratio; HAIC: Hepatic arterial infusion chemotherapy; PR: Partial response; SD: Stable disease; PD: Progressive disease.