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©2009 Baishideng.
World J Gastrointest Oncol. Oct 15, 2009; 1(1): 41-46
Published online Oct 15, 2009. doi: 10.4251/wjgo.v1.i1.41
Published online Oct 15, 2009. doi: 10.4251/wjgo.v1.i1.41
Figure 2 A schematic model of methylation spreading and gene silencing.
A: Status of completely unmethylated CpGs with gene transcription (arrow); B: Appearance of methylated CpGs at the edge of CpG islands with gene transcription (arrow); C: Gene silencing by CpG methylation at the transcription start site.
- Citation: Tamura G. Hypermethylation of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia. World J Gastrointest Oncol 2009; 1(1): 41-46
- URL: https://www.wjgnet.com/1948-5204/full/v1/i1/41.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v1.i1.41