Concept of chemoprevention in colorectal cancer

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Oct 15, 2009 (publication date) through Nov 3, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Oct 15, 2009; 1(1): 21-25
Published online Oct 15, 2009. doi: 10.4251/wjgo.v1.i1.21

Table 3 Colorectal cancer and the potential carcinogenic role of various factors

CRC category (% diagnosed with CRC)	Intervention strategies
Sporadic CRC (75%)	Screening Programmes
	Detection and removal of polyps (age > 50 yr)
	Role of chemoprevention
	NSAIDs/Aspirin
	5-aminosalicylate
	Dietary and lifestyle factors
	Good: low protein, high fibre, low fat, micronutrients, exercise
	Bad: alcohol, tobacco, obesity
Familial syndromes + miscellaneous (25%)	Screening colonoscopy
Familial syndromes + miscellaneous (25%)	Other: Aspirin and NSAIDs, 5-ASA

CRC: Colorectal cancer; NSAIDs: Non steroidal anti-inflammatory drugs; 5-ASA: 5-aminosalicylates; IBD: Inflammatory bowel disease.

Citation: O’Morain C, Qasim A. Concept of chemoprevention in colorectal cancer. World J Gastrointest Oncol 2009; 1(1): 21-25
URL: https://www.wjgnet.com/1948-5204/full/v1/i1/21.htm
DOI: https://dx.doi.org/10.4251/wjgo.v1.i1.21