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©2009 Baishideng.
World J Gastrointest Oncol. Oct 15, 2009; 1(1): 21-25
Published online Oct 15, 2009. doi: 10.4251/wjgo.v1.i1.21
Published online Oct 15, 2009. doi: 10.4251/wjgo.v1.i1.21
Table 1 Use of aspirin in average risk subjects and colonic neoplasia risk reduction
Study | n | Aspirin dose (mg/AD) | Study duration (yr) | Relative risk reduction (95% CI) |
Thun et al[13] | 622 424 | 100 mg3 | ≥ 1 | 0.58 (0.36-0.93)1 |
0.61 (0.38-0.97)2 | ||||
Gann et al[14] | 22071 | 325 | 5 | 1.15 (0.80-1.65)1 |
Cook et al[15] | 39876 | 100 | 10 | 0.97 (0.77-1.24)2 |
Stürmer et al[16] | 22071 | 325 | 12 | 1.03 (0.83-1.28) |
Giovannucci et al[17] | 47900 | 325 | 4 | 0.54 (0.34-0.84)1 |
Paganini-Hill et al[18] | 13979 | 325 | 7-10 | 1.38 (NR)1 |
Chan et al[19] | 89446 | 100 | 10 | 0.62 (0.44-0.86)2 |
Friis et al[20] | 29470 | 325 | 6 | 0.9 (0.70-1.10)1 |
García-Rodríguez et al[21] | 12005 | 325 | > 2 | 0.9 (0.8-1.1) |
Reeves et al[22] | 845 | 100 | > 5 | 0.79 (0.46-1.36)2 |
Juarranz et al[23] | 502 | 325 | NR | 0.32 (0.09-1.10) |
La Vecchia et al[24] | 3248 | 325 | 5 | 0.7 (0.50-1.00) |
Kune et al[25] | 1442 | 325 | NR | 0.57 (0.41-0.79) |
Suh et al[26] | 2704 | 325 | 6 | 0.33 (0.15-0.72) |
Slattery et al[27] | 3051 | 325 | > 5 | 0.7 (0.6-0.8) |
- Citation: O’Morain C, Qasim A. Concept of chemoprevention in colorectal cancer. World J Gastrointest Oncol 2009; 1(1): 21-25
- URL: https://www.wjgnet.com/1948-5204/full/v1/i1/21.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v1.i1.21