Copyright
©The Author(s) 2024.
World J Gastrointest Endosc. Mar 16, 2024; 16(3): 168-174
Published online Mar 16, 2024. doi: 10.4253/wjge.v16.i3.168
Published online Mar 16, 2024. doi: 10.4253/wjge.v16.i3.168
Table 1 Clinical characteristics of the patients, n (%)
Group P | n = 101 | Group C | n = 297 | ||
Age, median (range) | 75 | (48–93) | 75 | (40–90) | 0.8831 |
Sex | |||||
Male | 72 | (71.3) | 219 | (73.7) | 0.3676 |
Female | 29 | (28.7) | 78 | (26.3) | |
Diabetes mellitus | 17 | (16.8) | 41 | (13.8) | 0.7054 |
Chronic kidney disease on dialysis | 3 | (3.0) | 4 | (1.4) | 0.9287 |
Liver cirrhosis | 7 | (6.9) | 9 | (3.0) | 0.7777 |
Anti-platelet agents | 14 | (13.9) | 65 | (21.9) | 0.1485 |
Continuation | 3 | (3.0) | 18 | (6.1) | |
Discontinuation | 11 | (10.9) | 47 | (15.8) | |
Duration of re-starting, median (range) | |||||
Anticoagulants | 10 | (9.9) | 28 | (9.5) | 0.9355 |
Continuation | 3 | (3.0) | 6 | (2.0) | |
Discontinuation | 7 | (6.9) | 22 | (7.5) | |
Helicobacter pylori infection status | |||||
Not infected | 2 | (2.0) | 15 | (5.1) | 0.1524 |
Persistent infection | 27 | (26.7) | 92 | (31.0) | |
After eradIcation | 72 | (71.3) | 189 | (63.6) | |
Unknown | 0 | (0.0) | 1 | (0.3) |
Table 2 Characteristics of the lesions and treatment outcomes, n (%)
Group P | n = 101 | Group C | n = 297 | ||
Location 1 | |||||
U | 11 | (10.9) | 43 | (14.5) | 0.2573 |
M | 54 | (53.5) | 129 | (43.4) | |
L | 36 | (35.6) | 125 | (42.1) | |
Location 2 | |||||
L | 57 | (56.4) | 136 | (45.8) | 0.1295 |
G | 11 | (10.9) | 41 | (13.8) | |
A | 16 | (15.8) | 52 | (17.5) | |
P | 17 | (16.8) | 68 | (22.9) | |
Endoscopists | |||||
Expert | 30 | (29.7) | 154 | (51.9) | 0.0001 |
Non-expert | 71 | (70.3) | 143 | (49.4) | |
Resection time (min), median (range) | 64 | (10–320) | 68 | (7–445) | 0.0991 |
Resection size (mm), median (range) | 30 | (14–60) | 33 | (5–80) | 0.0106 |
En bloc resection | 100 | (99.0) | 295 | (99.3) | 0.7506 |
R0 resection | 95 | (94.1) | 274 | (92.3) | 0.2267 |
Post-ESD bleeding | 6 | (5.9) | 20 | (6.7) | 0.7804 |
Intraoperative perforation | 0 | (0.0) | 3 | (1.0) | 0.3106 |
Delayed perforation | 0 | (0.0) | 0 | (0.0) | - |
Aspiration pneumonia | 6 | (5.9) | 7 | (2.4) | 0.0801 |
Table 3 Factors involved in post-operative bleeding
Univariable OR | 95%CI | P value | Multivariable OR | 95%CI | P value | |
Pura Stat® application | 0.87 | 0.34–2.24 | 0.7806 | 1.28 | 0.28–2.15 | 0.6363 |
Endoscopists: Expert | 1.18 | 0.53–2.60 | 0.6904 | 1.14 | 0.36–2.12 | 0.7654 |
Resection size ≥ 50 mm | 7.05 | 2.86–17.34 | < 0.0001 | 6.63 | 2.52–17.47 | 0.0001 |
Anti-platelet agents | 1.88 | 0.79–4.51 | 0.1545 | 2.07 | 0.83–5.16 | 0.1185 |
Anticoagulants | 4.04 | 1.58–10.36 | 0.0036 | 3.49 | 1.26–9.69 | 0.0164 |
Table 4 Location of post-operative bleeding lesions, n (%)
Group P | Group C | P value | |
L | 5 (83.3) | 7 (35.0) | 0.735 |
A | 1 (16.7) | 3 (15.0) | 1 |
G | 0 (0.0) | 4 (20.0) | 0.566 |
P | 0 (0.0) | 6 (30.0) | 0.342 |
- Citation: Gomi K, Yamamoto Y, Yoshida E, Tohata M, Nagahama M. Using a novel hemostatic peptide solution to prevent bleeding after endoscopic submucosal dissection of a gastric tumor. World J Gastrointest Endosc 2024; 16(3): 168-174
- URL: https://www.wjgnet.com/1948-5190/full/v16/i3/168.htm
- DOI: https://dx.doi.org/10.4253/wjge.v16.i3.168