Colonoscopy quality with Entonox®vs intravenous conscious sedation: 18608 colonoscopy retrospective study

Table 2 Moderate-to-extreme against none-mild discomfort by analgesia/sedation type

Variable1	No. with moderate-to-extreme discomfort (%)2	Odds ratio (95%CI)1	P value1
Sedation type
Midazolam ± opioid	2137 (18.8)	Reference
Entonox ± opioid	689 (17.9)	1.06 (0.95-1.18)	0.27
Unmedicated	215 (11.4)	0.71 (0.60-0.83)	< 0.001
Age		1.00 (1.00-1.01)	0.08
Gender
Female	2114 (23.9)	Reference
Male	927 (11.3)	0.40 (0.36-0.43)	< 0.001

¹The dichotomous “moderate-to-extreme”/”none-mild” discomfort dependent variable was regressed on the sedation type, age, and gender independent variables using binary logistic regression. Output is expressed as odds ratios and P values;

²This column lists the number (simple percentage) of patients with moderate-to-extreme discomfort in each sedation type and gender group.