Impact of laparoscopic liver resection on bleeding complications in patients receiving antithrombotics

Figure 2 Perioperative management protocol (“Kokura Protocol”) for patients undergoing antithrombotic therapy in case of elective surgery. The management generally consists of interrupting ATT 5 to 7 d before surgery and early postoperative reinstitution in low thromboembolic risk patients. In patients with high thromboembolic risks, aspirin monotherapy is continued in patients with APT, and/or ACT was substituted by bridging heparin. ATT: Antithrombotic therapy; APT: Antiplatelet therapy; ACT: Anticoagulation therapy; Ope.: Operation; ASA: Aspirin; TPs: Thienopyridines.